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Excipients For Pharmaceutical Industry

Pharmaceutical excipients
The pharmaceutical industry is ever striving to satisfy patient’s therapeutical needs. Apart from active ingredients, pharmaceutical excipients have a major role in formulation development. The term “excipient” is derived from the Latin word excipere which means to except. Pharmaceutical excipients are everything other than the active pharmaceutical ingredients. Excipients are natural/ synthetic substances formulated alongside active ingredient of a medicine. These are included for bulking-up formulations which contain potent active ingredients.

Pharmaceutical Excipients are also useful in manufacturing process & aid in the handling of active substance concerned like by facilitating powder flow or non-stick properties while also aiding in vitro stability.

Types of Excipients

  • Antiadherents
  • Binders
  • Coatings
  • Colours
  • Lubricants
  • Disintegrants
  • Flavours
  • Glidants
  • Sorbents
  • Preservatives
  • Sweeteners
What Are Excipients Doing In Medicines?

Medicines are available in various dosage forms such as tablets, capsules, topical creams & gels, oral liquids, transdermal patches, implants, injectable products, inhalers & suppositories, eye products, and nasal products. Pharmaceutical excipients are the substances included in the pharmaceutical dosage not for their direct therapeutic action but to aid the manufacturing process as well as to protect and enhance stability. These are also helpful in bioavailability or patient acceptability. Thousands of excipients are widely used in almost 90% of medicines and make up products.

Some of the commonly used Excipients are:

Excipient
Use
Acacia Emulsifying Agent
Stabilizing Agent, Suspending Agent, Tablet Binder, Viscosity-Increasing Agent
Alginic Acid
Tablet Binder, Tablet Disintegrant; Viscosity-Increasing Agent
Alginate Binder
Stabilizing Agent, Suspending Agent
Aluminum Acetate
Antiseptic
Butyl Paraben
Antimicrobial Preservative
Benzyl Alcohol
Antimicrobial Preservative; Disinfectant; Solvent
Citric Acid
Disintegrant
Candelilla Wax
Binder
Calcium Carbonate
Tablet and Capsule Diluent; Therapeutic Agent
Croscarmellose Sodium
Tablet and Capsule Disintegrant
Carnuba Wax
Binder
Plain or Anhydrous Calcium Phosphate
Diluent
Carboxymethylcellulose Calcium
Tablet and Capsule Disintegrant
Corn Starch
Binder Stabilizing Agent, Suspending Agent
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